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TESAMORELIN | GH
TESAMORELIN | GH
5mg vial of TESAMORELIN
- Must purchase BACTERIOSTATIC WATER to mix.
Tesamorelin, also known as TH9507, is a synthetic growth hormone-releasing hormone (GHRH) analogue that has been studied for various medical purposes. In this review, we will explore its functions, uses, benefits, and standard research dosages.
Functions: Tesamorelin functions by stimulating the release of growth hormone (GH) from the pituitary gland. It specifically targets and activates the GHRH receptor, leading to an increase in GH secretion. Growth hormone plays a crucial role in various physiological processes, including growth, metabolism, and tissue repair.
Uses:
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HIV-Associated Lipodystrophy: Tesamorelin has been primarily investigated for its use in treating HIV-associated lipodystrophy, a condition characterized by abnormal fat redistribution in individuals with HIV infection. It has shown efficacy in reducing visceral adipose tissue (VAT) and improving body composition by redistributing fat from the abdominal region to peripheral areas.
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Metabolic Disorders: Tesamorelin may have potential benefits for individuals with metabolic disorders such as impaired glucose tolerance, insulin resistance, and dyslipidemia. It has shown positive effects on insulin sensitivity, lipid profiles, and markers of cardiovascular risk.
Benefits:
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Reduction of Visceral Adipose Tissue: One of the key benefits of Tesamorelin is its ability to reduce visceral fat accumulation, which is associated with increased cardiovascular risk and metabolic abnormalities. By targeting and reducing VAT, Tesamorelin may contribute to improved body composition and metabolic health.
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Improved Lipid Profiles: Research suggests that Tesamorelin treatment can lead to favorable changes in lipid profiles, including reductions in total cholesterol, LDL cholesterol, and triglycerides, as well as improvements in HDL cholesterol levels. These changes may contribute to a decreased risk of cardiovascular disease.
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Increased Insulin Sensitivity: Tesamorelin has demonstrated the potential to improve insulin sensitivity, which is important for maintaining normal glucose metabolism. By enhancing insulin action, Tesamorelin may help individuals with insulin resistance or impaired glucose tolerance.
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Body Composition Changes: Tesamorelin treatment has shown the ability to reduce abdominal fat and increase lean body mass, leading to a more favorable body composition. These changes can have positive effects on overall physical appearance and may improve self-esteem and quality of life.
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Potential Bone Health Benefits: Growth hormone is known to have an impact on bone health and mineral density. While more research is needed, Tesamorelin's ability to stimulate GH release may have potential benefits for bone health, particularly in individuals at risk of osteoporosis or age-related bone loss.
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Enhanced Cognitive Function: Some studies suggest that Tesamorelin may have positive effects on cognitive function, including improvements in memory and executive function. However, further research is necessary to fully understand this potential benefit.
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Reduced Liver Fat: Tesamorelin has shown promise in reducing liver fat content, which is associated with non-alcoholic fatty liver disease (NAFLD) and other liver-related conditions. By reducing liver fat, Tesamorelin may contribute to improved liver health.
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Potential Cardiovascular Benefits: In addition to improving lipid profiles, Tesamorelin may have direct cardiovascular benefits. It has been shown to reduce markers of inflammation and oxidative stress, which are important contributors to cardiovascular disease.
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Enhanced Quality of Life: Tesamorelin's ability to improve body composition, reduce fat accumulation, and potentially increase energy levels may lead to an improved quality of life for individuals with HIV-associated lipodystrophy or metabolic disorders.
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Potential Anti-Aging Effects: Growth hormone has long been associated with anti-aging effects, including improved skin quality, increased muscle mass, and enhanced vitality. While more research is needed, Tesamorelin's ability to stimulate growth hormone release may have implications for slowing down the aging process.
Tesamorelin may benefit bodybuilders and athletes by :
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Increased Muscle Growth: Tesamorelin's ability to stimulate growth hormone (GH) release may potentially contribute to increased muscle growth and hypertrophy, leading to improved muscle size and strength.
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Enhanced Recovery: Tesamorelin's potential to increase GH secretion may aid in the recovery process, promoting faster muscle repair and reducing downtime between intense training sessions.
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Improved Fat Metabolism: Tesamorelin has shown efficacy in reducing visceral adipose tissue (VAT). By promoting fat loss, it may help athletes achieve a leaner physique and improved muscle definition.
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Increased Energy and Stamina: GH is associated with improved energy levels and enhanced exercise capacity. Speculatively, Tesamorelin's potential to stimulate GH release may contribute to increased energy and stamina during workouts.
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Enhanced Endurance: Tesamorelin's speculated impact on GH secretion may have implications for improved endurance performance by increasing oxygen utilization, reducing fatigue, and enhancing aerobic capacity.
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Connective Tissue Strengthening: GH has been associated with improved connective tissue health. Tesamorelin's potential to increase GH levels may theoretically benefit bodybuilders and athletes by strengthening tendons and ligaments, reducing the risk of injuries.
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Improved Joint Health: GH is known to have positive effects on joint health and mobility. The speculated increase in GH levels from Tesamorelin may have implications for maintaining healthy joints and reducing joint pain.
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Accelerated Healing of Injuries: Tesamorelin's potential to stimulate GH release may support the healing process of injuries, potentially reducing recovery time and improving overall injury rehabilitation.
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Increased Protein Synthesis: GH promotes protein synthesis, which is crucial for muscle growth and repair. Speculatively, Tesamorelin's impact on GH release may support protein synthesis, leading to improved muscle recovery and development.
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Potential Anti-Aging Effects: GH has been associated with various anti-aging benefits, such as improved skin quality, increased collagen synthesis, and reduced wrinkles. Tesamorelin's speculated ability to stimulate GH release may have implications for maintaining a more youthful appearance.
Standard Research Dosages: In clinical studies, the standard dosage of Tesamorelin is typically 2 mg administered once daily as a subcutaneous injection. The treatment duration can vary depending on the specific condition being addressed and the goals of the study. It is important to note that Tesamorelin is a prescription medication and should only be used under the supervision of a qualified healthcare professional.
It's worth mentioning that Tesamorelin is not recommended for use in healthy individuals seeking to enhance performance, as its effects on muscle growth and athletic performance have not been extensively studied, and its use for such purposes is not approved.
Conclusion: Tesamorelin (TH9507) is a synthetic growth hormone-releasing hormone analogue with potential therapeutic benefits in conditions such as HIV-associated lipodystrophy and metabolic disorders. Its ability to reduce visceral adipose tissue, improve lipid profiles, increase insulin sensitivity, and potentially enhance bone health makes it an interesting area of research. Tesamorelin shows promise in improving body composition, cognitive function, liver health, and cardiovascular markers. As Tesamorelin is a prescription medication, it should only be used under medical supervision and in accordance with approved indications.
Application | A synthetic growth hormone releasing hormone analogue |
CAS | 218949-48-5 |
Molar Mass | 5136/mol |
Chemical Formula | C221H366N72O67S |
Amino Acid Sequence | Unk-Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-Gln-Gln-Gly-Glu-Ser-Asn-Gln-Glu-Arg-Gly-Ala-Arg-Ala-Arg-Leu-NH2 |
Synonyms | Tesamorelin
Egrifta 218949-48-5 TH9507 804475-66-9 |
Storage | Store in refrigerator at 4°C, tightly sealed, away from heat, light and moisture. |
Solubility | Soluble in water |
Organoleptic Profile | Fine white powder in 3mL glass aliquot |
Composition | Each aliquot contains Tesamorelin 5mg |
Specification | Tesamorelin content (per aliquot): Tesamorelin 5mg |
Terms | This material is sold for laboratory research use only. Terms of sale apply. Not for human consumption, nor medical, veterinary, or household uses. Please click the word Research Chemical to better understand what they are. *RESEARCH CHEMICAL. |
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